Print ISSN:-2581-5555

Online ISSN:-2456-9542


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Received : 19-06-2021

Accepted : 07-09-2021

Available online : 28-10-2021

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Chronobiology of hypertension and its chronotherapeutical management - A review

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Review Article

Author Details : Swathy V Krishna, S R Daisy P A*

Volume : 6, Issue : 3, Year : 2021

Article Page : 121-125

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Hypertension / High blood pressure is a very common disease and is a major risk factor for total organ failure, cardiovascular diseases (CVD) and premature death around worldwide. Prevalence of hypertension varies across regions and country and is dramatically variable in presentation. Sometimes it act as a silent killer i.e. the patients are unaware that they have the condition. According to estimation 46.5% of adults are unaware about their hypertensive condition, 36.9% are diagnosed and treated and the remaining 13.8% with hypertension have it under control. The investigation regarding the chronobiology, chronotherapy and chronopharmacology in treatment of hypertension began a long back ago. Hypertension is a lifestyle disease largely exhibit circadian variation. Also the condition is more evident to surge during early morning hours. Hence this requires chronotherapy. The chronobiology of hypertension along with its treatment in relation to the circadian variation is reviewed in this article.

Keywords: Hypertension, Chronobiology, Chronotherapy, Circadian rhythm, Chronopharmacology, ABPM

How to cite : Krishna S V, S R Daisy P A, Chronobiology of hypertension and its chronotherapeutical management - A review. IP Int J Compr Adv Pharmacol 2021;6(3):121-125

Copyright © 2021 by author(s) and IP Int J Compr Adv Pharmacol. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (

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